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胆汁酸在肝脏由胆固醇合成,是机体类固醇物质的主要清除途径,胆汁酸代谢在维持机体的胆固醇稳态中起重要的作用。本文就胆汁酸合成的机制、生理功能、肝肠循环、胆汁酸障碍相关疾病及胆汁酸合成的调节等方面的一些进展作一简要综述。
Abstract:Bile acids are synthesized from cholesterol in the liver,which represents a major pathway for net elimination of steroids from the body.Metabolism of bile acid biosynthesis,physical functions,enterohepatic circulation,and some advancement in factors on regulation of biosynthesis were shown.Besides,major diseases related to disfunction of bile acid biosynthesis homestasis were also introduced.
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基本信息:
DOI:
中图分类号:R333.3
引用信息:
[1]张久聪,聂青和.胆汁酸代谢及相关进展[J].胃肠病学和肝病学杂志,2008(11):953-956.
基金信息: